商店街は平日ひっそりしている。

English Translation

Shops are quiet on weekdays.

閑散としている(かんさんとしている)is a better collocation with 商店街 than ひっそりしている in this context.

  • 閑散とした means “quiet” and “idle/sluggish” (business operation). That means in this 商店街 (shopping district) context that there are few customers on weekdays.
  • ひっそりとしている means that there are actually customers in the shopping district, but they try not to make a noise.